MYC and cancer: The human c-myc oncogene is located distally in the long arm of chromosome 8, in the 8q24 region.28 Most human malignant tumors show amplification or overexpression of this gene, according to several studies.29 It is now known that the c-myc gene plays a part in several cell functions such as replication, growth, metabolism, differentiation and apoptosis.30