However, PPAR-γ immunostaining was significantly moreextensive and intense in tumor cells (mean: low group; 2.6±0.7, middlegroup; 2.7±0.9, high group; 3.3±1.0, P<.01)and in PIN (mean: 2.5±0.8, P<.01) than in tissue of BPH (mean:0.8±0.6).PPAR-γ staining was also high in blood vessels and stromaltissues of prostate cancer and PIN, with no significant difference between them(1.8–2.0). This evidence concerns the gene PPARG and benign prostatic hyperplasia.