When patients were stratified for the lowest CD4 lymphocyte count strata (CD4 ≤ 50 cels/mm3), all the imaging abnormalities previously associated to the diagnosis of disseminated TB (miliary infiltrate, pleural effusion, abdominal adenopathy, and splenic hypodense nodules) remained statistically significant for this diagnosis. The gene discussed is CD4; the disease is Pleural effusion.