Classically, PD has been associated with multiple causes ranging from post-encephalitic PD [1,2] to hereditary PD [3-7] in which genetic mutations have been associated such as, α-synuclein [5], parkin [4], DJ-1 [3], PINK1 [6], and LRRK2 [7]. This evidence concerns the gene PRKN and Parkinson disease.