Figure 3C shows the methylation pattern of 20 CpG sites on the second CpG island. The methylation levels in all VILIP-1 non-expressing SCLC were higher than those in NHBE and NCI-H520 cells. Thus, these data reveal an inverse correlation between the methylation status of VILIP-1 promoter and the respective gene expression in NSCLC cells. The gene discussed is VSNL1; the disease is small cell lung carcinoma.