In the first set of experiments, DC were separated on the basis of CD11c, CD8α and CD45RA expression into CD8α DC, pDC (CD11c+CD45RA+CD8α− DC) and DN DC and examined for their capacity to present MHC class I and II antigens at both 48 (Figure 5A,B) and 72 h (Figure 5C,D) after infection. The gene discussed is ITGAX; the disease is infection.