PRRT2 and glioblastoma: Indeed, treatment of the human glioblastoma cell line T98G with hypericin results in a significant inhibition of the cell invasion, an effect that is also obtained using specific PKC inhibitors [22], and a high level of PKCα expression in a human colon-adenocarcinoma cell line has been correlated with high migratory activity of colon carcinoma cells [23].