MMP9 and age-related macular degeneration: In addition, molecules suchas MMP-9 seem to be involved in both processes.Inhibition of MMP-9 in atherosclerotic lesions has been cited to opposeremodeling, as suggested by the inhibition of intimal thickening andoutward arterial remodeling [89]; while in AMD it is thoughtto be involved in microvessel formation duringearly phases ofangiogenesis, in the reabsorption ofneovascularization, and in involution andregression of vessels inlater stages [90].