PPARβ/δ agonistsare being developed for their ability to treat hyperlipidemia and they have thepotential to exert antithrombotic effects.It was recently published that platelets express PPARβ/δ aputative receptor for PGI2 whose activation inhibits plateletaggregation [64, 212–214]. The gene discussed is PPARD; the disease is hyperlipidemia.