In AP/SAP, glucocorticoid(represented by dexamethasone) mainly inhibits the generation and/or effect ofinflammatory mediators, enhances physical stress, improves microcirculation,alleviates endotoxemia, eliminates free radicals, and inhibits NO and NF-κB[35–37]. Here, NFKB1 is linked to serum lipopolysaccharide activity.