Recently, a novel cytokine, IL-31, was suggested to play an importantrole in pruritus in atopic dermatitis, as IL-31 caused the itch-associatedscratching behavior in conventional NC/Nga mice, an experimental animal modelfor atopic dermatitis [32].Whether this cytokine also participates in pruritus in psoriasis needs to bedetermined. The gene discussed is IL31; the disease is Pruritus.