Sugimoto et al. [4] showed thatelevated levels of TNFα mRNA in mice with TNBS-induced colitis can besuppressed by curcumin treatment, but Kwon et al. [7] found no significantchanges in TNFα mRNA levels in mice with DSS-induced colitis (treated oruntreated with plant flavonoid rutin). The gene discussed is TNF; the disease is colitis.