AKT1 and cancer: Previous studies have implicated the AKT/mTOR pathway in a diverse range of cancers including prostate (Kremer et al, 2006), lung (Lim et al, 2007), pancreas (Asano et al, 2005), colon (Nozawa et al, 2007) and oesophagus (Hou et al, 2007).