However, we note three exceptions from the overall trend: the highest levels of hY1, hY3 and hY4 overexpression were observed in kidney tumours, a very high level of hY5 overexpression in lung tumours, and no or borderline overexpression was observed for hY4 RNA in bladder, lung and prostate tumours (Figure 3). The gene discussed is RNY4; the disease is prostate neoplasm.