For example, in Table 1, "ad" is the abbreviation for "alzheimer disease"; "abeta" for "amyloid beta-peptide"; "apoe" for "apolipoprotein E"; "app" for "amyloid precursor protein"; "abeta42" for "beta-amyloid 42"; "mmse" for "Mini-Mental State Examination"; and "ps1" for "presenilin-1". The gene discussed is PSEN1; the disease is early-onset autosomal dominant Alzheimer disease.