Hypothermia, acidosis, drug-induced: administration of unfractionated or low-molecular-weight heparin, of factor Xa inhibitors, of thrombin inhibitors, or of asparaginase. Diseases with impairment of fibrin polymerization (for example, acquired factor XIII deficiency) or volume replacement solutions (HES, gelatine). The gene discussed is F10; the disease is hyperinsulinemic hypoglycemia, familial, 4.