GJB2 and hearing loss disorder: Recent studies found a 342 thousand base-pair (342 Kb) deletion close to the GJB6 [D(GJB6 - D13S1830)] gene, suggesting that this mutation could cause non-syndromic recessive hearing loss, either by a homozygous deletion or by digenic penetrance of the deletion in the GJB6 gene, associated with a trans mutation in the GJB2 gene in the heterozygous cases.24