MDK and cancer: However, it was noteworthy that only 42% of the late stage cancers and 8% of the early stage cancers were positive for MDK staining in the current study, while 79% of the biopsied cancers (including 89% of cancers with Gleason's pattern ≥ 4 and 68% of cancers with Gleason's pattern ≤ 3) were positive in the previous study [14].