A connection between p53, another tumorsuppressor gene, and PPAR-γ ligands has also been demonstratedby showing that 15-deoxy-PGJ2, together with docetaxel, stimulatesapoptosis in NSCLC through inhibition of Bcl2 and cyclin D1, and overexpressionof caspases and p53 [86]. Here, TP53 is linked to non-small cell lung carcinoma.