PPAR-γ is highly expressed in adipose tissue and it is a masterregulator of adipocyte differentiation [50, 51].In addition to its role in adipogenesis, PPAR-γ serves as an important transcriptional regulator of glucoseand lipid metabolism, and it has been implicated in the regulation of insulinsensitivity, atherosclerosis, and inflammation [52–54]. This evidence concerns the gene PPARG and atherosclerosis.