To confirm that the beneficial effect ofcurcumin in sepsis is mediated through PPAR-γ pathway, a separate group of animalswere treated for 3 days with PPAR-γ antagonist, GW9662, at 1.5 mg/kg alongwith curcumin at 0.24 μmol/kg body weight. This evidence concerns the gene PPARG and Sepsis.