PPARG and Sepsis: Inthat regard, Zingarelli et al.showed that PPAR-γ expression was markedly reduced in lungand thoracic aorta after CLP sepsis.Furthermore, in vivo treatment with 15d-PGJ2 or ciglitazone,one of the TZDs, following CLP ameliorated hypotension and survival, bluntedcytokine production and reduced neutrophil infiltration in lung, colon, andliver.