MicroCT indicated that 6of 7 mice surgically implanted with G292 cells (high VEGF expression) developeddetectable bone tumors at 2 weeks after tumor cell inoculation, whereas the HOScells-(low VEGFexpression) derived tumors became detectable in microCT images at either 4weeks or 6 weeks after inoculation (P<.05). The gene discussed is VEGFA; the disease is bone neoplasm.