No effects of the therapy on histologiclesions of the retinopathy were evaluated in diabetic animals, but micegenetically deficient in TNF were reported in an abstract to be protected fromgalactose-induced retinopathy [126].Epiretinal membranes obtained by vitrectomy, as well as cultured Mullerglial cells stimulated with glycated albumin or high glucose, showed increasedexpression of monocyte chemotacticprotein-1 mRNA and protein [127]. The gene discussed is TNF; the disease is retinal disorder.