iNOS expression is regulated at leastin part by NF-κB. Interestingly, experimentalsympathectomy itself increases gene and protein expression of iNOS in retinasof nondiabetic rats (78), suggesting that loss of sympathetic activity, such as which occurs in diabetes,might contribute to the upregulation of this inflammatory protein in theretina. Here, NFKB1 is linked to diabetes mellitus.