ICAM1 and diabetes mellitus: Diabetes increases expression of ICAM-1 in retinas of animals and humans [38, 49] and interaction of thisadhesion molecule on retinal endothelia with the CD18 adhesion molecule onmonocytes and neutrophils contributes to the diabetes-induced increase inleukostasis within retinal vessels [38].Leukostasis has been postulated to be a factor in death of retinalendothelial cells in diabetes [40].