In fact, cells lacking hMSH2 (Lovo colon cells and HEC59 endometrial adenocarcinoma cells), but not their nearly isogenic counterparts, in which an extra chromosome 2 has been reintroduced, failed to arrest in G2/M upon co-culture with activated PMNs (fig 2A). The gene discussed is MSH2; the disease is endometrium adenocarcinoma.