Multivariate analyses revealed that tumor size (HR 2.24, C.I. 1.10–4.53, p = 0.02), grading (G2 vs G1, HR 5.61, C.I. 1.25–25.30, p = 0.02 and G3 vs G1, HR 10.23, C.I. 2.07–50.45, p = 0.004), ErbB-3 expression (HR 2.16, C.I. 1.10–4.22, p = 0.024) and lack of ERβ1 (HR 3.28, C.I. 1.56–6.87, p = 0.002) were independent prognostic variables influencing DFS. Here, ERBB3 is linked to neoplasm.