A recent study [52] determined that the C(Glu) allele of the ERCC2 Lys751Gln variant allele marginally increased lung cancer risk (OR = 3.61, P = 0.04) in a Chinese population, and another identified [53] increased risk for squamous cell carcinoma of the head and neck in patients with the Gln/Gln genotype when compared with the Lys/Lys group. This evidence concerns the gene ERCC2 and head and neck squamous cell carcinoma.