Both – CVDs and bone metabolism disorders – might be causally linked in patients with chronic kidney disease (CKD), because the disturbances of the calcium-, phosphate-, vitamin D- and parathyroid hormone (PTH) metabolism, as well as the incidence of cardiovascular events as myocardial infarction rises early in the course of kidney disease [2, 3]. The gene discussed is PTH; the disease is metabolic bone disorder.