CD8A and infection: In support of this possibility, infection of mousepox-susceptible BALB/c mice with a highly attenuated strain of ECTV results in the induction of a strong T cell response (unpublished data), and depletion of NK cells does not affect the T cell response to the poorly pathogenic vaccinia virus (unpublished data) with which ECTV shares most of the dominant CD8+ T cell epitopes [57].