According to our present data, no differences in the expression of Ki-67, caspase-3, FHIT, CD44, P-GSK3β-ser9, MUC-2, MUC-5AC, MUC-6, and membrane β-catenin were observed between the intestinal and diffuse components of MT carcinomas, which supports the possibility of similar origin or dedifferentiation. This evidence concerns the gene CASP3 and cancer.