SLC7A5 and cancer: Whereas, LAT1 has been shown to mediate the uptake of a number of amino acid-related compounds such as L-dopa, triiodothyronine, thyroxin, and the anti-cancer agent melphalan (L-phenylalanine mustard, L-PAM, Alkeran, L-Sarcolysin) (Uchino et al, 2002).