PTGS2 and carcinoma: Likewise, high level of COX-2 predicted high MMP-9 level in carcinoma cells (OR 2.7, 95% CI 1.0–7.3), but laminin-5 γ2-chain staining within carcinoma cells was inversely associated with MMP-9 expression (OR 0.22, 95% CI 0.08–0.61).