RB1 and cervical intraepithelial neoplasia: We observed a progressive reduction in RBL2/p130 transcripts from NC to mild/moderate dysplasia and severe dysplasia suggesting that a reduction in RBL2/p130 may also be regulated at the transcriptional level in cervical preneoplasia and may be the first Rb family gene event in the development of cervical intraepithelial neoplasia.