Furthermore, a five-gene expression profile with VEGF, IL8 and the three genes (MYCN, SHH, and EREG) that we previously showed to be associated with outcome in the same series of IBCs [13] clearly delineated two subgroups of IBC with high (near 100%) and low (50%) relapse rates (Figure 3). The gene discussed is MYCN; the disease is inflammatory breast carcinoma.