Using clinical AIDS (Definition CDC 1987 and 1993), CD4 T cell counts below 200 cells/μl blood or viral RNA load above 104.5 copies per ml plasma as endpoint in Kaplan Meier and Cox proportional hazard analysis, no significant associations between the 136RQ or 136QQ genotype and the clinical course of infection were revealed (data not shown). Here, CD4 is linked to infection.