IL6 and head and neck squamous cell carcinoma: Including HNSCC patients only, Kaplan-Meier analysis showed that patients with high monocyte responsiveness to endotoxin, as measured by high IL-6 secretion (SFM), had decreased total (Fig. 4A) (χ = 4.3; p < 0.05) as well as disease-specific (Fig. 4B) (χ = 4.4; p < 0.05) survival compared to patients with low monocyte responsiveness.