EphB4 as well as ephrinB2 histoscores in cancer cells correlated with the corresponding mRNA levels in each case (EphB4, y=9.245x+133.49, r=0.522, P<0.001; ephrinB2, y=1.107x+147.57, r=0.561, P<0.001), as shown in Figure 2. The gene discussed is EPHB4; the disease is cancer.