breast cancer 1, early onset (its official name per Entrez Gene and the Human Gene Nomenclature Committee), as breast cancer susceptibility gene 1, or as the latter's variant breast cancer susceptibility gene-1. Similarly, breast cancer could be referred to as breast cancer, carcinoma of the breast, or mammary neoplasm. These variability issues challenge more sophisticated systems, as well; we discuss ways of coping with them in Text S1. This evidence concerns the gene ENSG00000279284 and breast carcinoma.