ENSG00000280371 and breast cancer: breast cancer 1, early onset (its official name per Entrez Gene and the Human Gene Nomenclature Committee), as breast cancer susceptibility gene 1, or as the latter's variant breast cancer susceptibility gene-1. Similarly, breast cancer could be referred to as breast cancer, carcinoma of the breast, or mammary neoplasm. These variability issues challenge more sophisticated systems, as well; we discuss ways of coping with them in Text S1.