In Sjögren's syndrome there are increased levels of inflammatory mediators (PGE2, thromboxane B2, IL-2 and IL-6) in saliva, which can assist in the diagnosis (Tishler et al, 1996, 1997; Streckfus et al, 2001; Kaufman and Lamster, 2002). This evidence concerns the gene IL2 and Sjogren syndrome.