Loss of chromosome 19p13.3, which includes the GNG7 locus, has been observed frequently in several cancers (Ritland et al, 1995; Hoglund et al, 1998; Wang et al, 1999; Kato et al, 2004; Miyai et al, 2004; Yang et al, 2004). The gene discussed is GNG7; the disease is cancer.