A recent study commissioned by the Department for Transport used formalized self reporting and continuous glucose monitoring to compare rates (proportion of patients experiencing an event) of hypoglycaemia prospectively over 9–12 months between patients with Type 2 diabetes treated with SU, patients with Type 2 diabetes treated with insulin for < 2 years and those treated for > 5 years, as well as patients with Type 1 diabetes diagnosed within the last 5 years and those with long duration (> 15 years) of Type 1 diabetes (see next section for insulin data) [35]. The gene discussed is INS; the disease is type 1 diabetes mellitus.