Our hypothesis that the P2Y12 H2 haplotype and SNPs in LD with the P2Y12 H2 haplotype would be associated with AMI was strengthened further by a report linking the P2Y12 H2 haplotype with coronary artery disease (CAD) [14], since myocardial infarction is the major complication of CAD [20]. This evidence concerns the gene P2RY12 and coronary artery disorder.