TP53 and ovarian cancer: These different subtypes of ovarian cancer are associated with different molecular characteristics: high grade serous cancers typically contain TP53 mutations [1,2], low grade serous carcinomas often have RAS-RAF pathway activation and mutations in the KRAS and BRAF genes [3], low-grade endometrioid cancers are associated with mutations in the beta-catenin gene, CTNNB1 [4], and mucinous cancers frequently have mutations in KRAS [5].