However, the publication of papers by van den Berghe [1] describing reduced mortality, morbidity and length of stay in surgical patients subjected to intensive insulin-therapy, as well as by Finney [3], demonstrating an association of hyperglycaemia with adverse outcomes in general intensive care, led most doctors at our institution to prescribe insulin to our ICU-patients with a therapeutic target set at a BG level of 4 to 8 mmol/L. Here, INS is linked to Hyperglycemia.