Genome-wide microarray analysis of RASF compared with NDSF revealed an induced expression of genes associated with the pathomechanism of RA including IL-1α, IL-1β, IL-8 and CXCL3, and treatment of RASF with frequently used anti-rheumatic drugs reverted the expression of numerous RA-related genes that were associated with cell growth, metabolism, apoptosis, cell adhesion, and inflammation [23]. Here, CXCL3 is linked to rheumatoid arthritis.