Unfortunately, we do not have comprehensive hormone levels for our patient, although one would expect her estrogen levels to be increased (due to obesity) and her FSH levels to be chronically decreased (due to pituitary axis inhibition); her ovaries were not polycystic and she was not hirsute, suggesting normal LH and androgen levels. This evidence concerns the gene PLOD1 and obesity due to melanocortin 4 receptor deficiency.