IL6 and colon carcinoma: The small 1,25-(OH)2D3-related increment of IL-6 production by COGA-1A cells seems to be without relevance for the anti-mitogenic and pro-differentiating effects of the hormone in human colon carcinoma cells [19], since 1,25-(OH)2D3 effectively suppressed IL-6-induced growth in differentiated Caco-2 cells (Figure 3).