In addition pharmacological [6,7] studies in animals, as well as post-mortem findings in schizophrenic patients [[8] but see [9]] show that expression of calcineurin is altered upon treatment with anti-psychotics and expression of the PPP3CC and other calcineurin subunits is decreased in the hippocampus of schizophrenic patients further implicating calcineurin in neuropsychiatric disorders, such as schizophrenia [10]. Here, PPP3CC is linked to schizophrenia.