All the tested cancer cells including HeLa, SiHa, SW756 and A549 expressed hTERT mRNA and telomerase activity, but the pharmacological inhibition of LSD1 activity or depletion of its expression was capable of further up-regulating hTERT mRNA and telomerase activity levels, which clearly indicates an identical inhibitory effect of LSD1 on hTERT transcription in both normal and cancer cells. This evidence concerns the gene KDM1A and cancer.