BIRC5 and neoplasm: Furthermore, survivin is also involved in radioresistance (Asanuma et al, 2002; Chakravarti et al, 2004; Rodel et al, 2005) and its suppression leads to an enhanced radiosensitivity in various malignant tumour cells (Pennati et al, 2003; Lu et al, 2004; Kappler et al, 2005).