PTGS2 and neoplasm: As showed in Table 1, there was no significant association between COX-2 expression and age (P = 0.383, Chi-Square test), histological type (P = 0.614, Chi-Square test), size of primary tumor (P = 0.837, Chi-Square test), c-erbB-2 status (P = 0.205, Chi-Square test) and PR status (P = 0.087, Chi-Square test).