MYC and Familial prostate cancer: The rs10808558 A allele showed an association with c-MYC overexpression in YRIs (expression difference of 0.23 log2 units, 95% confidence interval (CI) 0.06 – 0.41; P = 0.007) and this SNP is in low linkage disequilibrium (LD) with the prostate cancer risk variant rs1447295 (r2 = 0.19).